Not to mention that the F150 has the aerodynamics of a large brick with wheels.There are a ton out there. At least on YouTube.
4x4 obviously is going to out launch a Mustang on the street but they are heavier than a Mustang so it will take a bit more power in an F150 to go faster than a Mustang
I'll admit, I don't have any experience with the latest generation of F150's; but the 4wd F150's from at least 2004 to 2014 have vacuum operated lockouts (for lack of a better term) which disconnect each of the front hubs from the front CV shafts. This effectively prevents the front wheels from driving the CV shafts and spinning the front ring/pinion and driveshaft.The front driveshaft spins in 2WD